Effects and Optimization of Gamma-Amino Butyric Acid (GABA) Production Process using Glutamate Decarboxylase (GAD)
نویسندگان
چکیده
منابع مشابه
Identification and molecular cloning of glutamate decarboxylase gene from Lactobacillus casei
Gamma-amino butyric acid (GABA) possesses several physiological functions such as neurotransmission, induction of hypotension, diuretic and tranquilizer effects. Production of GABA-enriched products by lactic acid bacteria has been a focus of different researches in recent years because of their safety and health-promoting specifities. In this study, glutamate decarboxylase (gad) gene of a loca...
متن کاملProduction of GABA (gamma amino butyric acid) by Lactic Acid Bacteria
Gamma-amino butyric acid (GABA) is a kind of pharmacological and biological component and its application is wide and useful in Korea specially, becoming aging society in the near feature. GABA is request special dose for the purposed biological effect but the production of concentrated GABA is very difficult due to low concentration of glutamic acid existed in the fermentation broth. To increa...
متن کاملPartial Cloning and Nucleotide Sequencing of Glutamate Decarboxylase Gene Isoform 65 from Human Brain
Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA. The human brain has two isoforms of this enzyme, GAD65 and GAD67 that differ in molecular weight, amino acid sequence, antigenicity, cellular location ...
متن کاملidentification and molecular cloning of glutamate decarboxylase gene from lactobacillus casei
gamma-amino butyric acid (gaba) possesses several physiological functions such as neurotransmission, induction of hypotension, diuretic and tranquilizer effects. production of gaba-enriched products by lactic acid bacteria has been a focus of different researches in recent years because of their safety and health-promoting specifities. in this study, glutamate decarboxylase (gad) gene of a loca...
متن کاملIn developing Drosophila neurones the production of gamma-amino butyric acid is tightly regulated downstream of glutamate decarboxylase translation and can be influenced by calcium.
The presented work pioneers the embryonic Drosophila CNS for studies of the developmental regulation and function of gamma-amino butyric acid (GABA). We describe for the first time the developmental pattern of GABA in Drosophila and address underlying regulatory mechanisms. Surprisingly, and in contrast to vertebrates, detectable levels of GABA occur late during Drosophila neurogenesis, after e...
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ژورنال
عنوان ژورنال: KSBB Journal
سال: 2014
ISSN: 1225-7117
DOI: 10.7841/ksbbj.2014.29.6.426